Direct evidence for ProstaSol
No published randomised clinical trial of the finished formula was identified in the supplied material or our literature search. A proven PSA-lowering effect of ProstaSol cannot be inferred.
Botanical complex · 60 tablets
ProstaSol™: prostate research, explained transparently
A selected botanical combination – with a clear distinction between clinical evidence, laboratory findings and unanswered questions about PSA dynamics.
Food supplement. Not a substitute for diagnosis or medical treatment. A raised or rising PSA level requires medical assessment.
BCM-95™bioavailable curcumin
643 mgplant sterols daily
60tablets
4tablets per daily serving
12botanical components
2 weekssupply at standard use
Product profile
What is ProstaSol?
ProstaSol is a food supplement combining a broad range of botanical substances for men. The current formula includes plant sterols, BCM-95™ curcumin, LinumLife® lignans, quercetin, pygeum, ginseng, saw palmetto, resveratrol, Ganoderma and Polygonum cuspidatum extract.
ⓘ Important: studies on individual ingredients are not automatically evidence that the finished ProstaSol formula is effective. Dose, extract, combination, patient group and study duration can differ substantially.
Understanding PSA
What does research show about lowering PSA?
The scientific answer is nuanced. Some ingredients have limited clinical or preclinical signals; for others, high-quality trials explicitly found no PSA effect.
Curcumin
A randomised trial in prostate cancer during intermittent androgen deprivation found fewer PSA progressions during treatment, but no significant difference in absolute PSA change.
Flaxseed/lignans
A small pilot combining flaxseed with a low-fat diet reported lower PSA. The combined intervention, small sample and lack of a control group make attribution uncertain.
Saw palmetto
The large CAMUS trial found no difference from placebo in PSA changes, even at high doses.
Ganoderma/Reishi
A small randomised trial improved symptom scores but did not change serum PSA, prostate volume or urinary flow.
Quercetin, resveratrol and baicalein
Cell and animal models report effects on androgen signalling, PSA expression, inflammation or cell growth. These are not clinical efficacy data.
Current daily serving
The bioactive components
Amounts are for four tablets daily according to the current product information on med-pro.org. Most botanical images are from the supplied ProstaSol brochure.
Plant sterols
Beta-sitosterol, campesterol, stigmasterol and brassicasterol
643 mgClinical BPH trials report improvements in symptoms and urinary flow. They do not establish PSA lowering.
BCM-95™ curcumin
Curcuma longa
643 mgCurcumin has extensive preclinical research. Clinical PSA evidence is limited and inconsistent.
LinumLife® lignans
Linum usitatissimum
360 mgPilot and dietary studies provide signals on prostate biomarkers; evidence that lignans alone lower PSA is insufficient.
Quercetin
Flavonoid
150 mgLaboratory studies assess cell-cycle, inflammatory and androgen pathways. Clinical PSA efficacy has not been established.
Pygeum bark
Prunus africana
150 mgOlder controlled trials and reviews suggest benefit for LUTS/BPH, not specifically for PSA.
Ginseng extract
Panax ginseng · 15 mg ginsenosides
102 mgMechanistic data concern inflammation and androgen signalling. Robust clinical evidence for PSA lowering is lacking.
Saw palmetto extract
Serenoa repens
50 mgHigh-quality studies find no relevant effect on PSA; evidence for urinary symptoms is mixed.
Resveratrol & Polygonum
Polygonum cuspidatum
12.6 mg + 3.6 mg extractResearch is mainly preclinical and concerns inflammation and cell processes. No clinical PSA proof at the product dose.
Ganoderma extract
Ganoderma lucidum · Reishi
3.9 mgA small RCT improved IPSS symptoms but did not alter PSA or prostate volume.
Transparent formula
Ingredients per daily serving
Four tablets per day. Do not exceed the recommended daily intake.
| Component | Amount |
|---|---|
| Plant sterols | 643 mg |
| BCM-95™ DC (curcuminoids) | 643 mg |
| LinumLife® (flaxseed lignans) | 360 mg |
| Quercetin | 150 mg |
| Pygeum africanum bark powder | 150 mg |
| Ginseng extractincluding 15 mg ginsenosides | 102 mg |
| Calcium12% NRV | 101 mg |
| Phosphorus12% NRV | 79 mg |
| Saw palmetto extractSerenoa repens | 50 mg |
| Resveratrol | 12.6 mg |
| Ganoderma extract20:1 | 3.9 mg |
| Polygonum cuspidatum root extract50% resveratrol | 3.6 mg |
Primary sources
Selected scientific studies
Links open the PubMed record. The summaries identify design, findings and limitations – including neutral and negative results.
Randomised trial · 1995
Berges et al.: Beta-sitosterol in benign prostatic hyperplasia
Randomised and placebo-controlled: improved symptoms, urinary flow and residual volume; no relevant reduction in prostate volume. PSA lowering was not the efficacy finding.
Systematic review · 2002
Wilt et al.: Pygeum africanum for LUTS/BPH
Systematic review of mostly older, short trials: moderate benefit for symptoms and urinary flow; methodological quality and long-term evidence were limited.
Randomised trial · 2008
Noguchi et al.: Ganoderma lucidum for lower urinary tract symptoms
Small double-blind trial: improved IPSS, but no change in prostate volume, urinary flow or serum PSA.
Randomised trial · 2013
Andriole et al.: Saw palmetto and serum PSA (CAMUS)
369 men, up to three times the standard dose: PSA changes did not differ from placebo. Saw palmetto did not lower PSA.
Randomised trial · 2019
Choi et al.: Curcumin during intermittent androgen deprivation
97 patients: fewer had PSA progression during 6 months, but absolute PSA change and off-treatment duration did not differ significantly.
Randomised trial · 2010
Ide et al.: Isoflavones plus curcumin and PSA
Combination supplement in men after a negative biopsy: PSA fell only in a subgroup with baseline PSA ≥10 ng/mL. The independent contribution of curcumin is uncertain.
Pilot study · 2004
Demark-Wahnefried et al.: Flaxseed plus a low-fat diet – pilot study
Small uncontrolled pilot: PSA declined; the combined dietary intervention, small sample and absence of a control group prevent attribution to flaxseed or lignans alone.
Randomised trial · 2008
Demark-Wahnefried et al.: Flaxseed before prostatectomy
Randomised trial in 161 men: lower tumour proliferation rates in flaxseed groups. This is a tissue biomarker, not proof that ProstaSol lowers PSA.
Preclinical study · 2017
Xu et al.: Baicalein, androgen receptor and PSA expression
Cell-culture study: reduced androgen-driven PSA gene and protein expression. Preclinical data generate hypotheses and cannot establish clinical PSA lowering.
The studies assess individual compounds or different combinations, often at substantially different doses. Extrapolation to ProstaSol is limited.
Use & safety
Use with appropriate medical oversight
Suggested use
- Take two tablets twice daily with water before breakfast and dinner.
- Store in a cool, dry and dark place.
- Not intended for children or women.
- Contains soy.
When medical advice matters
- A raised, newly rising or fluctuating PSA.
- Ongoing cancer, hormone or urological treatment.
- Regular medication use – particularly before surgery or with anticoagulant medicines.
- New symptoms such as urinary retention, blood in urine, fever or severe pain.
Frequently asked questions
Clear answers
Has ProstaSol been proven to lower PSA?
Based on the reviewed material, no randomised clinical trial of the finished ProstaSol formula establishes PSA lowering. Findings for individual ingredients range from limited signals to clearly negative trials.
Is a falling PSA always beneficial?
No. PSA is a risk and monitoring marker whose interpretation depends on age, prostate conditions, inflammation, procedures and treatment. Changes should be assessed by the treating physician.
Can ProstaSol replace medical treatment?
No. ProstaSol is a food supplement and does not replace diagnostic testing, urological care or cancer treatment.
Why include negative studies?
Scientific transparency requires positive, neutral and negative findings to be shown together. This helps prevent laboratory or pilot findings from being overstated.
ProstaSol in the med-pro shop
Find current product details, availability and ordering options directly from med-pro Holland B.V.